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Chapter 1 advent (pages 1–10): J.R. Vane
Chapter 2 Ultrastructural association of the Alveolar?Capillary Unit (pages 11–36): Maya Simionescu
Chapter three Hypoxia and Pulmonary Vascular Endothelium (pages 37–60): Lynne Reid and Barbara Meyrick
Chapter four equipment for the examine of Lung Metabolism (pages 61–83): H.F. Woods, A. Meredith, G.T. Tucker and J.R. Shortland
Chapter five Substrate usage through the Lung (pages 85–104): H. Datta, W.A. Stubbs and K.C.M.M. Alberti
Chapter 6 Inactivation of Monoamines through the Lung (pages 105–128): M.B.H. Youdim, Y.S. Bakhle and R R. Ben?Harari
Chapter 7 The destiny of Circulating Biologically lively Peptides within the Lungs (pages 129–145): Sergio H. Ferreira, Lewis J. Greene, Maria Cristina O. Salgado and E.M. Krieger
Chapter eight The Lung as a Generator of Prostacyclin (pages 147–164): R.J. Gryglewski
Chapter nine Interrelationships among Prostacyclin and Thromboxane A2 (pages 165–183): S. Moncada and J. R. Vane
Chapter 10 rules of Pulmonary Arachidonic acid Metabolism through Anti?Inflammatory Steroids (pages 185–201): R.J. Flower
Chapter eleven Slow?Reacting elements and Their Structural Elucidation (pages 203–215): Priscilla J. Piper, Marwa N. Samhoun, J. R. Tippins, H. R. Morris and G. W. Taylor
Chapter 12 The Lung relating to Vasoactive Polypeptides (pages 217–237): Sami I. stated, Viktor Mutt and Ervin G. Erdos
Chapter thirteen Endocrine impacts on points of Lung Biochemistry (pages 239–250): Walter okay. Morishige
Chapter 14 Hormonal affects in the course of Fetal Lung improvement (pages 251–274): Philip L. Ballard
Chapter 15 Pulmonary Angiotensin?Converting Enzyme and Its Inhibition: A old Survey (pages 275–292): Y. S. Bakhle
Chapter sixteen Modulation of changing Enzyme task by means of Hypoxia and Its Physiological results (pages 293–311): S. Alex Stalcup, Joel S. Lipset and Robert B. Mellins
Chapter 17 Non?Respiratory services of the Lung within the Perinatal interval (pages 313–331): Robert B. Mellins, Dennis Davidson and S. Alex Stalcup
Chapter 18 Prostaglandin Receptors within the airlines (pages 333–350): H. O. J. Collier and P. J. Gardiner
Chapter 19 The Lung, Whole?Body Metabolism and ailment (pages 351–386): W. A. Stubbs and ok. G. M. M. Alberti

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Extra resources for Ciba Foundation Symposium 78 - Metabolic Activities of the Lung

Sample text

The terms ‘arteriole’ and ‘venule’ are best avoided since they are commonly given conflicting meanings. The term ‘preacinar’ describes all arteries proximal to the acinus - the respiratory unit supplied by a terminal bronchiolus (Fig. 1). The variety of segments and their different patterns of response constitute one theme that runs through this analysis of the response of the lung’s circulation to hypoxia; another concerns the neighbours of the endothelial cell - the smooth muscle cell and its precursor cells.

4). Study of the hypoxic response of the precapillary arterial unit has shown that the pericyte and intermediate cell are precursors of the smooth muscle cell (Meyrick & Reid 1978). The endothelial cell over the pre-acinar muscular arteries has as its nearest cell neighbour a muscle cell or one of its precursors, the intermediate muscle cell or the pericyte. It may be in direct contact with any of these neighbours. Only in some regions is the pericyte separated by a basement membrane; the intermediate muscle cell, by the basement membrane of each cell; and the smooth muscle cell by the two basement membranes and in addition the internal elastic lamina.

On this basis, per cell, activity was the same (Ody & Junod 1977). Stulcup: We compared converting enzyme activity in endothelial cell tissue cultures from aorta, pulmonary artery, some smaller systemic arteries, and systemic veins, including the vena cava. We also found no difference in activity, normalized to cell number. We also looked at endothelial cells in culture derived from lung by perfusion with collagenase and found no difference in enzyme activity between these cells and cultured endothelial cells from systemic arterial and venous sites.

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