By Matthew L. Crawley, Barry M. Trost
This booklet specializes in the drug discovery and improvement purposes of transition steel catalyzed techniques, which may successfully create preclinical and scientific drug applicants in addition to advertised drugs. The authors pay specific recognition to the demanding situations of transitioning academically-developed reactions into scalable commercial approaches. also, the booklet lays the basis for the way endured improvement of transition steel catalyzed approaches can convey new drug applicants. This paintings presents a special point of view at the functions of transition steel catalysis in drug discovery and improvement – it's a advisor, a historic potential, a pragmatic compendium, and a resource of destiny path for the sector
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Angew. Chem. Int. Ed. ; Gorelsky, S. ; Chung, B. K. ; Fagnou, K. J. Am. Chem. Soc. 2010, 132, 10692. ; Lassaletta, J. M. J. Am. Chem. Soc. ; Jones, G. ; Watson, D. ; Buchwald, S. L. J. Am. Chem. Soc. 2010, 132, 11278.  LaPlante, S. ; Edwards, P. ; Fader, L. ; Hucke, O. Chem. Med. Chem. 2011, 6, 505.  (a) For a selected review, see: Glorius, F. Angew. Chem. Int. Ed. 2008, 47, 8347; (b) Owston, N. ; Fu, G. C. J. Am. Chem. Soc. ; Fu, G. C. J. Am. Chem. Soc. 2010, 132, 1264.  (a) For a comprehensive review, see: Ley, S.
Dev. 2005, 9, 253.  For a selected example, see: Littke, A. ; Fu, G. C. J. Am. Chem. Soc. 2001, 123, 6989. -J. Angew. Chem. Int. Ed. 2010, 49, 4566.  (a) Watson, M. ; Jacobsen, E. N. J. Am. Chem. Soc. ; Ogoshi, S. J. Am. Chem. Soc. ; Sansano, J. M. Angew. Chem. Int. Ed. 2009, 48, 2452.  Reeves, J. ; Fandrick, D. ; Song, J. ; Yee, N. ; Senenayake, C. H. Org. Lett. 2010, 12, 4388.  (a) Littke, A. F. Modern Arylation Methods; Wiley-VCH: Weinheim, 2009; pp. ; Strom, A. ; Goddard, W.
1984, 25, 2823. Hawkins, J. ; Watson, T. J. N. Angew. Chem. Int. Ed. 2004, 43, 3224. Agbodjan, A. ; Cooley, B. ; Copley, R. C. ; Corﬁeld, J. ; Flanagan, R. ; Glover, B. ; Howes, P. ; Jackson, M. ; Matsuoka, R. ; Medhurst, K. ; Sharp, M. ; Slater, M. ; Toczko, J. ; Xie, S. J. Org. Chem. 2008, 73, 3094. Trost, B. ; Zhang, T. Eur. J. Org. Chem. 2011, 17, 3630. Trost, B. ; Andersen, N. G. J. Am. Chem. Soc. 2002, 124, 14320. (a) Maier, T. ; Fu, G. C. J. Am. Chem. Soc. 2006, 128, 4594; (b) Lee, E. ; Fu, G.